Preparation and Valuation of Capsules Containing Quercetin Phytosome for Hepatoprotective Activity

Quercetin is a well-known flavonoid with different biological effects such as anti-inflammatory, antioxidant, etc. However, this active ingredient was not applied broadly in clinical treatment due to the limitation of solubility, stability, and low oral bioavailability. To overcome limitation, phytosome quercetin prepared enhance quercetin's physicochemical properties permeability. In study, complexes were capsules evaluated hepatoprotective activity. The study found optimal formula containing content 50 mg that dissolved over 90% after 45 minutes. results evaluation activity mice also initially demonstrated had superior hepatoprotection compared those free quercetin.